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This combination medication is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. It may also be used with other diabetes medications.

This product contains 2 medications. Glyburide belongs to the class of drugs known as sulfonylureas. It lowers blood sugar by causing the release of your body's natural insulin and by decreasing the amount of sugar that your liver makes. Metformin works by decreasing the amount of sugar that your liver makes and that your stomach/intestines absorb. Both of these medications work by helping to restore your body's proper response to the insulin you naturally produce.

Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.
How to use Glucovance

Read the Patient Information Leaflet if available from your pharmacist before you start taking this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with meals as directed by your doctor, usually once or twice a day. Drink plenty of fluids while taking this medication unless otherwise directed by your doctor.

The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects (such as upset stomach and low blood sugar), your doctor may direct you to start this medication at a low dose and gradually increase your dose. Your doctor will adjust your dose based on your blood sugar levels to find the best dose for you. Follow your doctor's instructions carefully.

If you are already taking another anti-diabetic drug (such as chlorpropamide), follow your doctor's directions carefully for stopping the old drug and starting this combination medication.

If you are also taking colesevelam, take glyburide/metformin at least 4 hours before colesevelam.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

It may take up to 2 weeks before you get the full benefit of this drug. Tell your doctor if your condition does not improve or if it worsens (your blood sugar levels are too high or too low).
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